In this study, the essential oil and radical scavenging activity of o. The dpph free radical scavenging activities were expressed as a percentage of inhibition and results are shown in table 2. Determination of antioxidant and antimicrobial activities of. November 2003 original article antioxidant activity of otostegia persica labiatae and its constituents fariba shrififara, nargess yassaa, abbas shafieeb adepartment of pharmacognosy, school of pharmacy, tehran university of medical. Pdf antibacterial activity of otostegia limbata researchgate. Phytochemical study of essential oil of otostegia persica by gcmass and investigation of its methanol extract.
These molecules and their derivatives with a lactone group on the side chain or on the decaline system, have a great interest because of their biological properties as insect antifeedant, antiviral, cytotoxic and trypanocidal. Otostegia persica is called golder locally yassa et al. Hexagenia limbata, the giant mayfly, is a species of mayfly in the family ephemeridae. Synthesis of novel phenserinebasedselective inhibitors of butyrylcholinesterase for alzheimers disease qiansheng yu, harold w. Only three species are known in pakistan, otostegia limbata, otostegia persica and otostegia aucheri 20. Pdf two new acylated flavonol glycosides from the roots. Pdf antioxidant and antimicrobial potential of otostegia. It has been estimated that herbal medicines are used by more than 80% of the worlds population in developing countries to meet their primary healthcare needs. The present study was aimed at documenting the detailed ethnomedicinal knowledge of an unexplored area of pakistan.
Since ancient times, they have been largely employed in traditional medicine for their biological properties such as antimicrobial, antiinflammatory, antispasmodic, insecticidal, antimalaria. Otocorys alpestris deosai otostegia limbata otus bakkamoena ougeinia dalbergioides. Two new transclerodane diterpenoids from otostegia limbata. Ethnopharmacological relevance of medicinal plants used for the treatment of oral diseases in central punjabpakistan ethnopharmacological survey of medicinal plants used in traditional medicine by the communities of mount hermon, lebanon. Its leaves are opposite on stems with short petiole and obovate blade and covered with. This cited by count includes citations to the following articles in scholar. The study exposed 67 medicinal plant species used to prepare 110 recipes and the major modes of herbal formulation were decoction and powdering. A fairly large number of furanoditerpenoids have been reported from the families euphorbiaceae, fabaceae and. It is native to north america where it is distributed widely near lakes and slowmoving rivers.
The larvae, known as nymphs, are aquatic and burrow in mud and the adult insects have brief lives. Otostegia persica has been explored exhaustively for its phytochemical, pharmacological, and ethnopharmacological activities. Pdf the aim of this work was to examine the antimicrobial effect of. Ethnopharmacological documentation of medicinal plants. Size and shapecontrolled synthesis of bismuth nanoparticles. Medicinal plants used by traditional healers in kancheepuram district of tamil nadu, india. Keeping this in view, zno nanostructures znons have been synthesised through reduction by p. Ethnopharmacological documentation of medicinal plants used. A n area which is set aside by the national government for the protection of natural environment is known as a national park. Bupleurum falcatum and valeriana officinalis belongs to humid regions, while forsskalea tenacissima, lavandula angustifolia and otostegia limbata belongs to subhumid regions. Facile biosynthesis of agnps using otostegia limbata plant. Literature selection for the current study a large number of published and unpublished research studies related to the ethnomedicinal, phytochemical and antis. They are all biologically active and were subjected to the phytochemical isolation and characterization.
The 2 genera ballota and otostegia, belonging to the lamiaceae family, are closely related taxonomically and found mainly in the mediterranean area, middle east, and north africa. Chapter 1 microbiology microorganism louis pasteur. Diversity and use of ethnomedicinal plants in the region of. Scanning electron microscope sem studies expose that agnps formation is highly homogenous and spherical with. Treatment of imines 5, 14, and 24 derived from the c 19diterpenoid alkaloids with nano 2 naoachoac afforded a series of novel rearrangement diterpenes 68, 1519, and 2527, respectively. Application of ethnobotanical indices on the use of. Facile biosynthesis of agnps using otostegia limbata.
Chemical composition and antioxidant activity of otostegia. Pdf antioxidant and free radical scavenging potential of. In total, extracts from 34 ethnomedicinally valuable pakistani plants were reported. Ethnopharmacological documentation of medicinal plants used for hypertension among the local communities of dir lower, pakistan. Antioxidant and antimicrobial potential of otostegia limbata l and ajuga bracteosa l against pathogenic microorganisms. Two new acylated flavonol glycosides from the roots of otostegia limbata. A new genus was erected for the 4 yellowflowered species of otostegia otostegia integrifolia benth.
Jun 16, 2016 furanoditerpenoids are a special group of diterpenoids composing of one or more furan rings, which are rarely found in nature. Chemical investigation of otostegia limbata full text. In pakistan, the available modern healthcare services are either insufficient or inaccessible. Greensynthesised cerium oxide nanostructures ceo 2 ns. Furanoditerpenoids are a special group of diterpenoids composing of one or more furan rings, which are rarely found in nature. Nitrogen free extract 57 gross energy 57 total digestible nutrients 57. The total flavonoid content of methanol extract was 416. Antioxidant and free radical scavenging potential of otostegia limbata article pdf available in asian journal of chemistry 226. These molecules and their derivatives with a lactone group on the side cha. It is commonly grown all over pakistan and in kashmir kale et al.
Structure, diversity, and regeneration potential of monotheca. Otostegia genus consists of about 33 species table 1 which grows mainly in the mediterranean region and adjoining asia minor khan et al. The blade is bluish greyishgreen, oblanceolate to lanceolate shaped, and reaches 29 cm long 3, 4. Some of these compounds have anticancer, antibacterial, antiviral, and antioxidant activity. The genus otostegia belongs to family lamiaceae and consists of more than 31 species growing in asia and mediterranean region 19. Leaves of lantana camara and otostegia limbata were showed the maximum and minimum quantity of. Synthesis of novel phenserinebasedselective inhibitors. Silver nanoparticles agnps synthesized through reduction by otostegia limbata green extract are, hereby, reported for the first time.
The structure elucidation of the new compounds was based primarily on twodimensional 2d nmr. Plants are an important source of traditional medicine for the treatment of various diseases. Disinfection group 3 free download as powerpoint presentation. Antioxidant and free radical scavenging potential of otostegia limbata.
The toxicological evaluation of otostegia limbata was done against the third instar larvae of drosophila melanogaster meigen for 24hours of exposure. Room temperature preparation of chloro,difluoroethenylzinc reagent cf 2 cclzncl by the metalation of hcfc. The ones marked may be different from the article in the profile. Medicinal plants have always been part of human culture and have the potential to cure different diseases caused by microorganisms. Materials and methods plant material otostegia persica burm. Otostegia is a genus of flowering plants in the family lamiaceae, first described in 1834. To grapple with multidrug resistant bacterial infections, implementations of antibacterial nanomedicines have gained prime attention of the researchers across the globe. Scanning electron microscope sem studies expose that agnps formation is highly homogenous and. Facile biosynthesis of agnps using otostegia limbata plant extract. Nowadays, zinc oxide zno at nanoscale has emerged as a promising antibacterial therapeutic agent. It is native to eastern africa and the middle east species.
The labdane, halimane and clerodane type diterpenoids are compounds that have been isolated in plants of several families. Introduction libata is a library used inside the linux kernel to support ata host controllers and devices. Traditional medicines and their invitro proof against staphylococcus aureus in pakistan muhammad adnan 1, akash tariq 2, roqaia bibi 1, sakina mussarat 1, bibi fatima 1, nawab ali 3, hazir rahman 4, zabta khan shinwari 5 1 department of botany, kohat university of science and technology, kohat 26000, pakistan 2 key laboratory of mountain ecological restoration and. Agarofurane, a new c 15 compound from the essential oil of asarum europaeum l. Chapter 1 microbiology free download as powerpoint presentation. Since ancient times, they have been largely employed in traditional medicine for their biological properties such as antimicrobial, antiinflammatory, antispasmodic, insecticidal, antimalaria, etc. Proximate analysis total protein, fats, carbohydrate, ash, and moisture contents were carried out following methods of association of official analytical chemists. In addition, the thiophene nucleus has been used in the synthesis of a variety of heterocyclic compounds. Journal of the bombay natural history society pdf free. This compound has been characterized by means of ftir, 1hnmr, cnmr, and. It is very interesting to observe that in this case, o. If the address matches an existing account you will receive an email with instructions to retrieve your username. Structure, diversity, and regeneration potential of.
Koi booi, spina ghazai, chotta kanda otostegia a spiny shrub, mostly found in waste and dry pakistan hazara, swat, chitral, kurram, peshwar, rawalpindi, salt. Pdf the plants provide medicinally valuable substances since ancient. A novel thiophenecontaining compound, 2acetyl3amino52oxopropylsulfanyl4cyanothiophene 4 was synthesized by reaction of malononitrile with cs2 in the presence of k2co3 under reflux in dmf and the subsequent reaction with chloroacetone followed by cyclization. Two new tricyclic clerodanetype diterpenoids, limbatolide d 1 and limbatolide e 2, have been isolated from the roots of otostegia limbata. This article aims to provide an overview of the chemical constituents present in o. The reaction conditions are further modified to produce bi nanorods and nanoplates. Free radicals also attack dna and cause mutation leading to cancer 3. Due to their interesting and versatile biological activity, thiophenecontaining compounds have attracted the attention of both chemists and medicinal chemists. Apluda mutica, aristida adscensionis, heteropogon contortus, chrysopogon aucheri and. Since ancient times, they have been largely employed in traditional medicine for their biological properties such as antimicrobial, antiinflammatory, antispasmodic, insecticidal, anti.
Oct 06, 20 bupleurum falcatum and valeriana officinalis belongs to humid regions, while forsskalea tenacissima, lavandula angustifolia and otostegia limbata belongs to subhumid regions. Phytochemical analysis and comprehensive evaluation of. The extracts from the leaves of otostegia integrifolia have been reported to show phytochemical analysis, total flavonoid content, antioxidant and antibacterial activities. Locally in lower dir it is called as spin azghay and grows best in dry habitats hedge, 1990. Three new tricyclic cisclerodane type diterpenoids trivially named as limbatolide a 1, limbatolide b 2 and limbatolide c 3 have been isolated from the roots of otostegia limbata along with two known compounds. Two new flavonol glycosides from otostegia limbata benth. Chemical composition and antioxidant activity of otostegia persica.
The total flavonoid content of the extracts expressed as quercetin equivalent mgqe per dry sample table 2. Holloway, tadanobu utsuki, arnold brossi, and nigel h. Pharmacological aptitude and profiling of active constituent. Otostegia integrifolia is a shrub which grows up to 3 m tall, often with paired spines at the nodes. Tramea limbata wikispecies wikispecies, free species. In pakistan, biologists are mainly focusing on plants antimicrobial activities against escherichia coli due to its increasing resistance to antibiotics. In last three decades, a number of new antibiotics have been produced by pharmacological industries but the toxic effects and the global emergence of multidrug resistant mdr of microbes is limiting.
The study exposed 67 medicinal plant species used to prepare 110 recipes and the major modes of herbal. Aularches scabiosae autophila cerealis amseli cymaenotaenia limbata avena fatua avicennia sp axiopaena maura ay thy a fuligula fuligula. Our results revealed that the total flavonoid content of methanol and ethyl acetate extracts is 416. May 18, 2018 the extracts from the leaves of otostegia integrifolia have been reported to show phytochemical analysis, total flavonoid content, antioxidant and antibacterial activities. As it was observed from the table, both methanol and ethyl acetate extracts of the leaves of o. Diterpene lactones with labdane, halimane and clerodane. The results varied from 8 to 90% for mc extracts and 3. The two extracts also showed good antioxidant activity as well. This study reports on the multivariate analysis of the vegetation of hindukush range in pakistan, concentrating on the structure and regeneration potential of monotheca buxifolia and associated tree species. Pdf pharmacological aptitude and profiling of active constituent. Determination of antioxidant and antimicrobial activities. According to the world conservation union it is a natural area selected in order to protect the ecological integrity of one or more ecosystems for the present and upcoming generation ahmad and ann, 2011.
Diversity and use of ethnomedicinal plants in the region. Qaisar maqbool ab a national institute of vacuum science and technology ninvast, ncp complex, islamabad, pakistan. In iran, only three species are available, otostegia aucheri, o. Archive of sid iranian journal of pharmaceutical research 2003 235239 received.
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